UC SAN DIEGO · FEIST LAB
Biological Automation Biofoundry
We offer access to our unique automation, the ALEbots, our high-throughput Adaptive Laboratory Evolution (ALE) capabilities along with sequencing analysis to both academic and industry through collaborative projects and fee-for-service work.
The Machines
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What is a Biological Automation Biofoundry?
A biofoundry built for automated evolution
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See inside
A look inside the biofoundry
Get a glimpse of the space behind our lab’s research.
services we offer
Advanced automation and computational tools for biological discovery.
Automated EvolutionRun evolution experiments at scale.
Automated Evolution
Leverage ALEbots to automate long-term adaptive laboratory evolution experiments with precise environmental control, continuous monitoring, and high-frequency sampling. Our automated platforms enable experiments that would be difficult or impractical to run manually.
Strain EngineeringBuild better strains, faster.
Strain Engineering
Combine experimental evolution, genome-scale modeling, and data-driven approaches to improve microbial strains for desired phenotypes. We can help identify promising engineering strategies and uncover the genetic changes underlying improved performance.
Custom ExperimentsDesign experiments around your goals.
Custom Experiments
Work with our team to develop experimental workflows tailored to your organism, research question, and desired outcomes. From defining experimental conditions to running and monitoring the experiment, we can adapt our automation infrastructure to fit your needs.
Data & ModelingTurn experimental data into insight.
Data & Modeling
Connect high-frequency experimental measurements with bioinformatics and computational modeling to understand how organisms adapt and predict what changes may lead to improved performance. These insights can be used to guide new experiments and accelerate the design-build-test-learn cycle.
how to work with us
Bring us a question. Let’s build the experiment together.
01
Get in Touch
Share the research question, strain, pathway, or evolution challenge you’re looking to tackle.
02
Find an Approach
We’ll work with you to determine how adaptive laboratory evolution, strain engineering, modeling, or our automation platforms could fit your project.
03
Design the Experiment
Together, we’ll define the conditions, populations, measurements, and experimental strategy needed to answer your question.
04
Run at Scale
Our ALEbots can run many independent populations in parallel, with automated sampling and high-frequency measurements over long experiments.
05
Analyze & Iterate
We combine experimental data with computational analysis to understand what changed, identify useful mutations or phenotypes, and guide the next round of experiments.
01
Get in Touch
Share the research question, strain, pathway, or evolution challenge you’re looking to tackle.
02
Find an Approach
We’ll work with you to determine how adaptive laboratory evolution, strain engineering, modeling, or our automation platforms could fit your project.
03
Design the Experiment
Together, we’ll define the conditions, populations, measurements, and experimental strategy needed to answer your question.
04
Run at Scale
Our ALEbots can run many independent populations in parallel, with automated sampling and high-frequency measurements over long experiments.
05
Analyze & Iterate
We combine experimental data with computational analysis to understand what changed, identify useful mutations or phenotypes, and guide the next round of experiments.
See our second location
Our research at DTU
Expanding our automated research across the Atlantic
At DTU, our lab continues to develop and apply automated approaches to microbial evolution and engineering. Our Denmark-based biofoundry extends the capabilities of Feist Lab and creates new opportunities for collaboration and discovery.
At DTU, our lab continues to develop and apply automated approaches to microbial evolution and engineering. Our Denmark-based biofoundry extends the capabilities of Feist Lab and creates new opportunities for collaboration and discovery.
Inside our DTU biofoundry
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HAVE AN EXPERIMENT IN MIND?
Build your next experiment with us.
Have a research question, strain, or experiment you’d like to explore? Get in touch with us to see how Feist Lab’s automation, evolution, and modeling capabilities could help.
Lab Locations
San Diego, CA
University of California San Diego
Copenhagen, Denmark
Technical University of Denmark
Get in Touch
In accordance with applicable Federal and State law and University policy, the University of California does not discriminate, or grant preferences, on the basis of race, color, national origin, religion, sex, disability, and/or other protected categories. More information about Proposition 209 can be found here. More information about the University of California Anti-Discrimination Policy can be found here. Initiatives are open to all eligible members of the UC San Diego campus community and does not discriminate against, or grant preferential treatment to, any individual or group on the basis of race, color, national origin, religion, sex, disability, and/or other protected categories.
©2026 by Adam Feist and UC San Diego. All rights reserved.
Lab Locations
San Diego, CA
University of California San Diego
Copenhagen, Denmark
Technical University of Denmark
Get in Touch
In accordance with applicable Federal and State law and University policy, the University of California does not discriminate, or grant preferences, on the basis of race, color, national origin, religion, sex, disability, and/or other protected categories. More information about Proposition 209 can be found here. More information about the University of California Anti-Discrimination Policy can be found here. Initiatives are open to all eligible members of the UC San Diego campus community and does not discriminate against, or grant preferential treatment to, any individual or group on the basis of race, color, national origin, religion, sex, disability, and/or other protected categories.
©2026 by Adam Feist and UC San Diego. All rights reserved.